Test a heart pacing treatment for Chagas-related heart failure
Part of Heart & circulation, Infections clinical trials.
This study looks at a heart treatment called cardiac contractility modulation in people with Chagas heart disease who have moderate symptoms and weak heart pumping. It aims to see whether this therapy improves heart function and related outcomes in the right patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to under 75 years old and able to sign consent before any study tests
- You need recent lab proof of Chagas infection from at least two different blood tests in the last 2 years
- You must have heart failure symptoms that are NYHA class II or III (not class IV) and a weak heart pumping level (LVEF under 35%)
- Your heart’s electrical/strain measurements must meet the study needs (not left bundle branch block, plus required desynchrony and strain results)
- You should not join another study right now (or have joined one that ended within the last year) unless it’s unrelated observation
- You must not have certain major health problems (for example: significant kidney/liver disease, moderate/severe lung disease, uncontrolled diabetes with complications, or severe nerve disease)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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