Heart Resynchronization Therapy With Electrical Mapping Guidance
Part of Heart & circulation clinical trials.
This trial tests a heart device (CRT) that coordinates your heart's contractions, combined with a new electrical mapping technique to place leads more precisely. It's designed for people with weak heart function and abnormal electrical patterns who haven't improved enough with medications alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart rhythm is normal (sinus rhythm), not irregular like atrial fibrillation
- Your heart pumps weakly (ejection fraction ≤35%) and your heartbeat is slow or wide on an ECG, OR you have an ejection fraction ≤40% with expected pacing >20%
- You have heart failure symptoms (shortness of breath, fatigue, or limitations with activity)
- You've been on optimal heart failure medications for at least 3 months
- You've never had a pacemaker, defibrillator, or CRT device implanted before (with rare exceptions)
- You don't have recent heart attacks, strokes, severe valve disease, or kidney/liver failure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial evaluates a noninvasive way to assess who should get Cardiac Resynchronization Therapy (CRT), and to check results after implantation. If you fit the heart rhythm and heart pump criteria, the approach may help confirm whether CRT is appropriate for you.
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This trial compares two types of pacemaker placement to improve heart function in people with heart failure. One method paces the heart's natural conduction system, while the other paces the lower chambers of the heart. The goal is to find which approach works better for heart resynchronization therapy.
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