Personalized lower-dose radiation for HPV-related throat cancer
Part of Cancer, Ear, nose & throat, Mouth & dental clinical trials.
This Phase 2 study tests whether giving a less intense (de-escalated) radiation plan can work for certain people with HPV-related oropharyngeal throat cancer. It uses HPV blood testing and scans to help guide treatment, aiming to keep cancer control while reducing treatment side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older
- You have confirmed squamous cell cancer in the oropharynx (throat area), or it’s strongly suspected
- Your initial plan is curative treatment with either surgery through the mouth plus neck dissection, or chemo-radiation with cisplatin
- Your scans within the last ~16 weeks do not show cancer spread to distant organs
- You can do study follow-ups at the study hospital and complete questionnaires by yourself (or with help)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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