Clin2
NCT05541276Possibly a fitRecruiting

Melatonin to prevent waking confusion in young children after surgery

Emergence Delirium

Treatments studied

Part of Brain & nervous system, Mental health, Pain clinical trials.

This study tests whether giving melatonin before surgery can help prevent agitation and confusion in young children after they wake up from anesthesia. Participation may help your child have a smoother recovery after their procedure.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
676 people
Ages
1 year to 6 years
Study type
Interventional

Who can take part

  • Child is between 1 and 6 years old
  • Surgery is planned and expected to last at least 30 minutes under general anesthesia
  • No known allergy to melatonin or its components
  • Child is not currently taking melatonin daily

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05091242Recruiting· Phase 2/Phase 3
Preventing agitation after anesthesia in babies up to 1 year old

This study tests a way to reduce post-surgery agitation (confusion or restlessness) in babies aged 3 to 12 months who need anesthesia for a procedure. The goal is to make recovery calmer and safer for your baby.

Perth, Nedlands
NCT07655817Recruiting· Phase 2/Phase 3
Magnesium for reducing confusion after surgery in children

This trial tests if giving magnesium through the mouth works as well as through the vein to prevent confusion or agitation right after surgery in children having their tonsils out. It aims to find a simpler way to help kids wake up calmly.

Tanta, Gharbia Governorate
NCT05800639Recruiting
Testing brain-wave patterns during pediatric anesthesia awakening

This study looks at brain-wave activity (measured with sensors) in young children during and after general anesthesia for planned eye surgery. It may help doctors understand why some children become very upset or confused as they wake up.

Seoul
NCT07046364Recruiting· Phase 4
Remimazolam for confusion after pediatric brain surgery

This study tests a medicine called remimazolam to see if it reduces confusion and agitation (emergence delirium) when children wake up from brain surgery. It may help your child have a smoother recovery.

Beijing, Beijing Municipality
NCT06545890Recruiting· Phase 1/Phase 2
Ketofol vs. dexmedetomidine for preventing confusion after waking in kids having eye muscle surgery

This study compares two medicines (Ketofol and dexmedetomidine) to see which better prevents confusion and agitation when children wake up from squint eye surgery. The goal is to find a safer, more comfortable recovery for your child.

Cairo
NCT07345715Recruiting
Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children

This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.

Tanta, El-Gharbia

Hear when a new Emergence Delirium trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.