Testing nerve-to-muscle signal changes to diagnose movement diseases
Part of Bones, joints & muscles, Brain & nervous system, Hormones & metabolism, Infections clinical trials.
This study measures how nerves communicate with muscles, using recordings and gels. It aims to spot early, personalized signs of conditions like ALS and related diseases, and to improve diagnosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- If you’re a patient, you have one of these diagnoses: ALS, PLS, PMA, SMA, polio, or MS
- You can understand the study and sign informed consent
- You are able to physically take part in the recording session
- If you have a psychiatric condition, it must not be active right now
- You don’t have severe nerve damage linked to conditions like poorly controlled diabetes
- You have no known allergy or strong reaction to the recording environment, equipment, or the gels used
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether whole-body electrical muscle stimulation (using small electrodes on the skin) can help adults with certain neuromuscular diseases exercise and improve muscle strength. It may be an option if you can stand for about 15 minutes at a time and have some muscle strength left.
This study uses a very powerful MRI scanner (7T) to take detailed pictures of the brain and spinal cord in people with motor neuron disease. The goal is to find non-invasive markers that could help diagnose and monitor the disease.
This study uses a quick, painless electrical test to measure muscle health in people with nerve or muscle disorders and in healthy volunteers. It aims to learn how these measurements change over time, which may help diagnose and monitor these conditions better.
This study measures how well your nerves and muscles work together to see if it can serve as an early sign (a “biomarker”) of ALS. It may help doctors track ALS more accurately, especially in people who already seem to have ALS based on nerve testing.
This study continuously measures activity and movement in people with ALS and in control participants. It aims to better understand how muscle disease changes day-to-day function, which may help improve future monitoring or care.
This study tests a device that records muscle activity (EMG) in healthy volunteers and critically ill patients in the ICU. It aims to learn how well the device works in different groups, which could help monitor muscle function in the future.
Hear when a new Spinal Muscular Atrophy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.