Amniotic membrane treatment for advanced jaw bone loss
Part of Bones, joints & muscles, Mouth & dental clinical trials.
This Phase 2 trial studies whether a human amniotic membrane dressing can help heal stage II maxillomandibular osteonecrosis of the jaw (MRONJ). It focuses on people who developed MRONJ after certain cancer-related bone treatments and who may need surgery and antibiotics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 years or older
- You have stage II MRONJ in the upper jaw (maxilla), confirmed by exam and imaging
- Your MRONJ happened in the setting of a tumor and you previously received medicines such as bisphosphonates, denosumab, and/or anti-angiogenics
- If you can become pregnant, you use reliable birth control; if you’re postmenopausal, you’re eligible
- You can sign informed consent and you have French social security coverage
- You do not have a short life expectancy (less than 6 months), and your cancer or mouth condition is not rapidly worsening
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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