Light therapy for mouth GVHD after a stem cell transplant
Part of Immune system & allergy clinical trials.
This Phase 2 study tests a special light treatment (photobiomodulation) to improve oral graft-versus-host disease (GVHD) after a stem cell transplant. It may help people whose mouth symptoms have not improved with at least one prior treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your child) had a stem cell transplant from another person (allo-HCT)
- You are age 4 or older
- You have oral GVHD in the mouth with a moderate-to-severe score (OMRS) of 3 or higher
- Your oral GVHD has not responded to at least one prior treatment, including steroid mouth treatments
- You have not changed your whole-body (systemic) immune-suppressing medicine type or dose in the last 2 weeks
- If you use any other mouth treatments, your dose and schedule have been stable for at least 2 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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