Clin2
NCT05688488Possibly a fitRecruiting

Curcumin to help prevent vocal cord scar adhesions after surgery

Glottic Web of LarynxLaryngeal StenosisGlottic CarcinomaLaryngeal LeucoplakiaLaryngeal PolypLaryngeal Papilloma

Treatments studied

Part of Ear, nose & throat, Genetic & congenital, Lungs & breathing clinical trials.

This trial tests whether curcumin (a natural compound) can reduce scar-like “adhesions” that can form between both vocal cords after endoscopy surgery. If you’re having a procedure on both vocal cords, this could help lower the chance of postoperative sticking and related voice problems.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
100 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have a condition affecting both vocal cords and you are scheduled for endoscopy surgery on both sides.
  • Alternatively, you have scar-like adhesion on both vocal cords and you need endoscopy incision to open it up.
  • You do not have other non–vocal-cord diseases in the larynx (voice box).
  • You should not have serious heart or lung problems that affect breathing or blood flow.
  • You must be able to return for follow-up visits on time after surgery.
  • You must be willing to sign consent and follow the study plan.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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