Voice outcomes after laser surgery vs radiation for early vocal cord cancer
Part of Cancer, Ear, nose & throat, Lungs & breathing clinical trials.
This trial compares two treatments—CO2 laser surgery through the mouth versus one-vocal-cord irradiation—for early-stage larynx (voice box) cancer. It aims to see which option better preserves voice quality after treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are well enough for daily activities (ECOG 0–1)
- You have a confirmed, previously untreated early cancer on one vocal cord (stage 0 or I) in the voice box
- Your team can reach the tumor through the mouth for laser surgery and can remove it with a safe buffer (about 2 mm) without crossing to the other cord
- Your baseline voice tests are documented before starting treatment
- You can safely handle both study treatments (surgery and radiation) and complete follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding immunotherapy before surgery, followed by either radiation or organ-preserving surgery, can improve outcomes for people with locally advanced laryngeal or hypopharyngeal cancer. It may help avoid complete removal of the voice box.
This study compares ways of treating early squamous cell cancer in the tonsil or the tongue base, using either radiation therapy, transoral (through-the-mouth) surgery, or both. It aims to see which approach works best while keeping cancer under control.
This study tests a precise, MRI-guided radiation treatment for early-stage vocal cord cancer. It aims to deliver high-dose radiation more accurately to the tumor, possibly reducing side effects and improving outcomes.
This study tests if a shorter course of radiation (hypofractionated) works as well as the standard longer course for people with early-stage cancer of the vocal cords. The goal is to find a treatment that is more convenient and has similar results.
This trial studies whether adding radiation therapy after surgery can help people with early-stage voice box cancer that has poor differentiation (cells look very abnormal). It aims to improve outcomes for this specific type of cancer.
This study tests a shorter, higher-dose radiation schedule for people with early glottic cancer. It might mean fewer trips to the hospital and less burden on your voice box.
Hear when a new Larynx Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.