Micro-packaged liver cell transplant for adult liver failure
Part of Digestive system clinical trials.
This Phase 1 study tests a new way to place liver cells (in small protective “micro-packages”) inside the belly to treat liver failure. It aims to see whether the treatment is safe and potentially helps liver function in adults with worsening chronic or acute-on-chronic liver failure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old and weigh more than 40 kg (about 88 lb)
- You have liver failure that is not improving after at least 3 days of standard care
- Your blood tests show liver failure signs (for example, bilirubin is elevated but not extremely high, and clotting tests are abnormal enough to meet the study range)
- You may have complications like fluid buildup (ascites) and/or confusion from liver disease (hepatic encephalopathy)
- You must not have certain unsafe conditions like bleeding in the brain, active bleeding, or uncontrolled severe infection
- You cannot have pregnancy or breastfeeding, and you cannot test positive for HIV or SARS-CoV-2
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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