Proton radiation for cancer spread into the covering of the brain
Part of Brain & nervous system, Cancer clinical trials.
This trial tests proton radiation to treat cancer that has spread into the thin lining around the brain and/or spinal cord (leptomeningeal metastasis). It may help control disease in that area while aiming to better protect surrounding healthy tissue.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cancer spread into the leptomeningeal space around the brain and/or spinal cord.
- The spread has been confirmed by MRI scan or by a CSF fluid test (cytology).
- You can have the study doctors verify that you’re well enough to participate (Karnofsky score 60 or higher).
- Your blood counts need to meet minimum levels (hemoglobin, neutrophils, and platelets).
- You can give consent, and if you can become pregnant you must use effective birth control; if you’re pregnant or breastfeeding, you can’t join.
- You must be able to get MRI of the brain and spine using contrast dye (gadolinium).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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