Clin2
NCT07789912Possibly a fitNot yet recruiting

Proton radiation that avoids memory areas for cancer spread in the fluid

Leptomeningeal MetastasisBreast CancerLung Cancer (NSCLC)

Part of Brain & nervous system, Cancer, Lungs & breathing, Skin clinical trials.

This study tests a special type of proton radiation that avoids the memory centers of the brain, called memory-avoidant proton craniospinal irradiation. It is for people with cancer that has spread to the fluid around the brain and spinal cord, and it aims to treat the cancer while potentially protecting memory and thinking.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older and have been diagnosed with cancer that has spread to the fluid around your brain and spinal cord (leptomeningeal metastases).
  • You have breast cancer or non-small cell lung cancer, or another solid tumor cancer that has spread to the fluid.
  • You are able to care for yourself and are not bedridden (score of 60 or higher on a standard health scale).
  • You have adequate bone marrow function (your body can make enough blood cells).
  • If you are a woman who could become pregnant, you agree to use effective birth control; if you are a man, you also agree to use effective birth control.
  • You are able to have an MRI of the brain and spine with contrast (dye).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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