Brain radiation, immunotherapy, and chemo for lung cancer spread
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a combination of low-dose radiation to the whole brain, immunotherapy, and chemotherapy given through a lumbar puncture. It is for people with lung cancer that has spread to the lining of the brain and has not responded to standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have lung cancer that has spread to the lining of the brain or spinal cord (leptomeningeal metastasis).
- Standard treatments for your lung cancer have stopped working.
- Your cancer outside the brain is not growing (stable disease).
- You are willing to undergo radiation to the brain, immunotherapy, and chemotherapy via lumbar puncture.
- You do not have an active autoimmune disease or serious health problems like uncontrolled heart or kidney failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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