Compare two focused radiation plans for limited brain metastases
Part of Brain & nervous system, Cancer clinical trials.
This trial compares two types of focused radiation—treating only the visible spots versus using a larger but still controlled radiation approach—for people with a small number of brain metastases. It may help find which plan controls tumors while limiting side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cancer confirmed by pathology (not blood cancers like leukemia/lymphoma)
- Your treatment plan is aimed at treating or preventing spread after surgery with focused, divided radiation sessions
- You have 1 to 3 brain metastases total, with the largest one no bigger than about 4 cm, based on an MRI
- Your overall health is good enough for treatment (ECOG 0–2 or KPS 70 or higher)
- You have no signs of tumor spread near the hippocampus (about within 5 mm) on MRI
- You have no prior brain/head radiation that included stereotactic radiosurgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at people with a small number of brain metastases who are treated with a focused, staged form of radiation after surgery or to treat the cancer. It may help doctors better understand how well this approach works and who benefits most.
This trial compares two types of radiation for people with small cell lung cancer that has spread to the brain (10 or fewer spots). One approach uses focused radiation only on the tumors, the other treats the whole brain while trying to protect memory. The goal is to see which works better with fewer side effects.
This trial compares two ways of giving radiation to the brain for people with 5 or more brain metastases: focused stereotactic radiosurgery, or a whole-brain approach that tries to spare the memory area (with memantine). It aims to see which method better protects thinking and memory while still treating the tumors.
This trial compares two ways of giving focused radiation for brain metastases: before surgery or after surgery. It aims to see which timing works better to control tumors while keeping you safe.
This Phase 1 study tests a form of focused radiation given in stages to shrink larger brain metastases. It may help people whose tumors are in the brain but not suited to whole-brain radiation alone, while also checking safety and how well the treatment can be delivered.
This study compares giving focused, high-dose radiation before surgery versus after surgery for people with large brain metastases. The goal is to see which timing works best to control the tumors and help neurological outcomes.
Hear when a new Brain Oligometastases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.