Study drug effects on blood vessels and organs in heart surgery
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 18 years old
- Have elective open-heart surgery through a chest incision (sternotomy or thoracotomy)
- Be able to take vericiguat (or not be intolerant to it)
- Not be taking other similar blood-vessel medicines or certain erection medicines (PDE-5 inhibitors)
- Not be pregnant or breastfeeding
- No severe kidney problems or recent kidney dialysis (kidney replacement therapy)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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