Biologic gum treatments added to non-surgical cleaning
Part of Mouth & dental clinical trials.
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have gum disease (periodontitis) stage III or IV with grade A to C
- You don’t currently smoke; if you used to smoke, you quit at least 1 year ago
- You haven’t had any gum treatment in the last 3 months
- You have at least one deep intrabony defect seen on x-ray (deep gum pocket and enough bone defect depth) and it is a one- or two-wall defect
- You are not pregnant and you can sign informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether one of two treatments can improve healing of “intra-bony” gum/bone defects around teeth after deep cleaning. It may help some people with periodontal disease who have pockets deep enough to involve the bone but with certain health and dental conditions.
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
This trial tests a new way to treat deep gum pockets caused by periodontitis using a special gel (RGD) applied without cutting the gums. It may help rebuild bone and improve gum health with less discomfort than traditional surgery.
This study compares two ways to fix deep gum pockets around teeth: a laser (MIST) or a traditional scalpel (GBT). Both methods use a gel made from your own blood (PRF) to help healing. The goal is to see which works better.
This study tests whether a new dental gel used along with deep gum cleaning (scaling and root planing) can improve periodontitis. If you qualify, you would receive standard gum treatment plus the study gel, then be followed over time.
This trial studies an “autologous platelet concentrate” (a gel made from your own blood) to help heal deep bone defects caused by periodontitis. It’s meant for adults with specific measurements in one or more gum pockets and bone areas after recent non-surgical gum treatment.
Hear when a new Periodontal Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.