External drainage for severe TBI brain swelling
Part of Brain & nervous system, Injuries & trauma clinical trials.
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 65 years old.
- Your injury is severe, with Glasgow Coma Scale (GCS) of 3 to 8.
- Your pupils are the same on both sides and both respond to light.
- Your brain CT shows limited midline shift (5 mm or less) and open (not fully blocked) fluid spaces around the brain.
- You can start the procedure within 24 hours after injury, and you have a qualifying ELD safety score (5 or higher).
- There is no reason you can’t receive the tube, such as bleeding/clotting problems, very low platelets, blood thinners, pregnancy, or certain spinal shape issues.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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