CPM therapy vs bone overgrowth in hip or knee
Treatments studied
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This study compares continuous passive motion (a machine that gently moves a joint without you moving it) versus the body’s tendency to form extra bone called heterotopic ossification. It aims to see whether CPM can affect how and how much bone overgrowth develops after neurologic injuries like stroke, brain injury, or spinal cord injury.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a recent neurologic injury such as stroke, traumatic brain injury, or spinal cord injury, and your condition is stable
- A leg ultrasound test you had is negative for a blood clot (deep vein thrombosis, or DVT)
- A bone scan is positive for early bone overgrowth (heterotopic ossification) after symptoms start
- If bone overgrowth is confirmed in your hip or knee, you must be able to get a CT scan to measure it
- You can safely receive gentle joint motion using a CPM machine (no life-threatening issues that would make it unsafe)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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