Optimizing electroconvulsive therapy settings
Part of Brain & nervous system clinical trials.
This study looks at how to best set the electrical stimulation for electroconvulsive therapy (ECT), a treatment for severe depression and other mental health conditions. The goal is to improve how well ECT works while possibly reducing side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently receiving electroconvulsive therapy (ECT) at Pennsylvania Hospital.
- You are willing and able to take part in the study.
- You agree to also participate in the SWEET COMBO protocol, which involves optical monitoring during ECT.
- You do not have other significant mental health conditions that could affect the study's safety or results.
- You have not had a poor response to ECT in the past that would make the study risky or not beneficial for you.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies better ways to deliver ECT (electroconvulsive therapy) for people with difficult-to-treat depression, including some people with bipolar depression. You may be offered an ECT strategy that’s tailored to your situation, with the goal of improving outcomes and reducing problems.
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This study tests a way of adjusting (titrating) ECT treatment to improve outcomes in people with major depression or bipolar II. It’s mainly for those who already need ECT with right-side electrode placement.
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