Imaging study to spot early spine changes in at-risk children
Part of Blood & lymphatic, Bones, joints & muscles, Genetic & congenital, Heart & circulation, Hormones & metabolism clinical trials.
This study uses MRI and physical measurements to look for early signs of scoliosis (a side-bending of the spine) in children who are at higher risk. It may help doctors understand when scoliosis starts and improve early monitoring.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are the right age: 8, 9, or 10 years old (with some exceptions by sex/group).
- You’re in one of these risk groups: an older sibling/twin/parent with AIS, or you have 22q11.2 deletion syndrome (22q11.2DS).
- A physical exam shows no scoliosis signs right now (forward-bending test and a measurement under a 7° threshold).
- A parent/legal guardian can give written consent for the study.
- You can safely have an MRI scan (no MRI contraindications).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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