Bone-cartilage transplant for ankle joint cartilage damage
Part of Bones, joints & muscles clinical trials.
This trial studies an “autologous” transplant, meaning using your own bone and cartilage, to treat painful cartilage damage in the ankle (on the talus). It may help people whose ankle cartilage injury is deep, has not improved with non-surgical care, and meets specific side and health requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have painful talus cartilage damage (Hepple stage V) that is at least 5 mm deep
- Your ankle function score is 80 points or less (AOFAS)
- You tried non-surgical treatments for at least 6 months without enough improvement
- The injury is only on one side (one ankle) and there is no matching damage on the shin/tibial side
- You do not have certain related joint problems or conditions (like ankle arthritis with narrowing, gout in the ankle, osteoporosis, or leg deformity)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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