Clin2
NCT05951517Possibly a fitRecruiting

Mycophenolate for stubborn stomach Purpura (HSP) in children

Henoch-Schönlein PurpuraGastrointestinal InjuryMycophenolate Mofetil

Part of Blood & lymphatic, Heart & circulation, Immune system & allergy, Skin clinical trials.

This trial looks at whether mycophenolate mofetil can help children ages 3–18 who have Henoch-Schönlein purpura affecting the gut that does not improve with steroid treatment. It may help reduce serious stomach symptoms like severe belly pain, bleeding, or bowel problems.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
24 people
Ages
3 years to 18 years
Study type
Interventional

Who can take part

  • Be between 3 and 18 years old
  • Have a confirmed diagnosis of HSP (Henoch-Schönlein purpura) with digestive (gut) symptoms
  • Have “refractory” gut HSP—your symptoms did not respond to IV steroid treatment, or came back when steroids were being lowered
  • A parent/guardian agrees to the study and signs consent
  • Have no known allergy to mycophenolate mofetil (MMF)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03647852Recruiting
Study for difficult IgA vasculitis with gut symptoms

This study looks at treatment strategies for children with IgA vasculitis (also called Henoch-Schönlein purpura) when it mainly affects the stomach and intestines and symptoms do not improve with standard steroid dosing. It may help find better ways to control the illness early and prevent serious complications.

Shanghai
NCT06568549Recruiting· Phase 4
Reducing Immunosuppression in Older Kidney Transplant Patients (RIOT Trial)

This trial tests whether older kidney transplant recipients can safely reduce their immunosuppression medications using a special monitoring tool called Trugraf. If you are over 55, have had a stable transplant, and want to possibly lower your medications, this study may be for you.

Phoenix, Arizona
NCT05937880Recruiting
Leflunomide for kids with stubborn Henoch-Schonlein purpura rash

This trial looks at whether leflunomide can calm Henoch-Schonlein purpura (a childhood rash condition) when the rash is hard to control. If standard treatments don’t stop new or worsening rash, this study may offer another option.

Guangzhou, Guangdong
NCT05538208Recruiting· Phase 2
Children with lupus kidney inflammation using mycophenolate

This Phase 2 study tests how well the medicine mycophenolate mofetil (MMF) works for children and teens with lupus nephritis that is “proliferative” (a specific biopsy type). You may qualify if your kidney biopsy and current treatment match the study’s targets and you can follow frequent visits and testing.

San Francisco, California
NCT07734012Not yet recruiting· Phase 2
Adding mycophenolate after stem cell transplant for scleroderma

This trial is testing whether adding the drug mycophenolate after your stem cell transplant can improve the treatment of systemic sclerosis (scleroderma). It may help people who are already undergoing this transplant to have better outcomes.

Ottawa, Ontario
NCT07785128Not yet recruiting· Phase 2
Mycophenolate mofetil for hard-to-treat IgA nephropathy

This trial is testing whether the drug mycophenolate mofetil can help people whose IgA nephropathy hasn't improved with standard treatments. It aims to reduce protein in the urine and protect kidney function.

Dhaka

Hear when a new Henoch-Schönlein Purpura trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.