Testing centhaquine for low-blood-pressure shock patients
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies whether centhaquine is safe and can help treat adults in the emergency room or ICU who have hypovolemic shock (dangerously low blood pressure from low circulating fluid). Participants receive the usual shock care, and the study adds this medicine to see if outcomes improve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and are in the emergency room or ICU for shock
- Your systolic blood pressure is 90 or lower when you arrive, and you’re still receiving standard shock treatment
- Your blood lactate level is greater than 2.0 mmol/L, suggesting hypovolemic shock
- You are not pregnant
- You did not have CPR before joining the study, and there is no “do not resuscitate” order
- You are not in another medication/intervention study, and you don’t have major ongoing illnesses like sepsis, advanced cancer, chronic kidney/liver failure, advanced heart failure, or AIDS that were present before the trauma
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medicine called centhaquine to help raise blood pressure and improve blood flow in people with severe low blood pressure due to fluid loss (hypovolemic shock). It is given alongside the standard emergency care you would already receive.
This Phase 3 study tests whether starting a blood-pressure medicine earlier in the emergency room can improve outcomes for people with low blood pressure or shock. It focuses on patients who have already received enough IV fluids and meet specific blood pressure and lab findings.
This study tests a new drug called centhaquine for people with severe breathing problems (ARDS) in the ICU. The drug may help improve oxygen levels and recovery, and the study compares it to the usual care alone.
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
This study tests whether giving low-dose blood pressure medicines through a standard IV (instead of a larger central line) is safe and effective for patients with shock in the intensive care unit.
This trial tests whether using a blood test called renin to guide treatment can help stabilize blood pressure in ICU patients with shock. It may help doctors choose the right medications and targets to reduce complications.
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