Endocalyx for heart failure with fluid overload
Part of Heart & circulation clinical trials.
This Phase 2 study tests Endocalyx to treat people with heart failure who currently show signs of fluid buildup (congestion). If you qualify, you may help researchers see whether this supplement can improve symptoms and heart-failure–related measurements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have heart failure, especially with reduced or mildly reduced heart pumping (reduced ejection fraction).
- You have recent signs of fluid overload, such as high NT-proBNP blood test, swelling, breathing difficulty when lying flat, or an evidence of overload on chest X-ray (plus other specific options).
- Your “water pill” (diuretic) and blood pressure medicine plan has been stable for at least 3 weeks.
- You must be able to give informed consent (or your legal representative can), before any study procedures start.
- You are age 18 or older.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a wearable device that removes extra fluid from your body without using the kidneys. It may help people with heart failure who still have fluid buildup despite taking high doses of water pills.
This trial tests a new treatment called Endocalyx for people whose high blood pressure doesn't get better with multiple medications. It aims to see if Endocalyx can help lower blood pressure when standard medicines aren't enough.
This trial studies a treatment that removes extra fluid through a catheter placed in the abdomen (peritoneal ultrafiltration) for people with “cardio-renal syndrome” (heart and kidney problems together). It may help those who stay congested despite high-dose water pills (diuretics) and have certain heart circulation and fluid signs.
This trial is for people hospitalized with heart failure and signs of fluid overload, such as swelling or fluid in the lungs. It aims to check if patients still have extra fluid when they go home, which may help improve their recovery.
This trial studies a device (the Nephronyx System) used in the hospital to treat worsening heart failure with fluid buildup, especially when diuretics (water pills) aren’t working well. It aims to check the device’s safety and whether it performs as expected to help patients get better.
This trial tests a device to help the kidneys remove excess fluid in people hospitalized for worsening heart failure who are not responding well to standard diuretic (water pill) therapy. It aims to improve heart and kidney function.
Hear when a new Chronic Heart Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.