Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 399 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06736574RecruitingPhase 3
Study of omecamtiv mecarbil for chronic heart failure with very weak heart pump
This study tests an investigational medicine (omecamtiv mecarbil) for people with chronic heart failure and very low pumping strength. It looks at whether the drug can help prevent heart failure events or the need for stronger treatments.
Alexander City, AlabamaAges 18–85 - NCT07038356RecruitingPhase 3
Continuing empagliflozin during heart failure hospitalizations
This study tests whether continuing empagliflozin (a heart failure medicine) during a hospital stay for heart failure is beneficial compared to stopping it. Participation may help improve recovery and reduce complications.
Jena, ThuringiaAges 18 years+ - NCT07574593Recruiting
Heart Failure Sensor Implant Study
This study tests a small sensor placed in a vein to help monitor and manage heart failure. The sensor tracks fluid buildup in your heart and may help doctors adjust your treatment to keep you feeling better and out of the hospital.
Chula Vista, CaliforniaAges 18 years+ - NCT06601465RecruitingPhase 2
Vericiguat for cognitive health in heart failure
This study tests whether the heart failure medication vericiguat can also improve thinking and memory in people with heart failure who have mild cognitive problems. It involves taking vericiguat pills and having brain scans to track changes.
Calgary, AlbertaAges 18 years+ - NCT07714252Enrolling by invitation
Virtual palliative care team for veterans with heart or lung disease
This study tests a virtual team of nurses and social workers who provide palliative care to veterans with heart failure, COPD, or interstitial lung disease. The goal is to improve quality of life by offering extra support at home.
Phoenix, ArizonaAges 18 years+ - NCT07547540RecruitingPhase 1
Study of an investigational drug for heart failure
This study tests an experimental drug called LY3971297 to see if it can help people with chronic heart failure. It aims to find out if the drug is safe and if it improves heart function.
Detroit, MichiganAges 18–65 - NCT06469814Enrolling by invitation
Heart failure snapshot study
This study is a snapshot of patients with heart failure and aims to better understand how heart failure is managed in different settings, from outpatient care to emergency treatment.
YerevanAges 18 years+ - NCT07232030Recruiting
Barostim device for heart failure treatment
This trial tests a device called Barostim, which is implanted under the skin to stimulate nerves that help control heart failure. It's for people with mild to moderate heart failure whose symptoms are not fully controlled by medications.
Mobile, AlabamaAges 18 years+ - NCT05650541Recruiting
Testing a home device to help chronic heart failure
This study tests whether a CardioPulmonary Management (CPM) system device used at home is safe and can improve outcomes for people with chronic heart failure. It may help manage symptoms and reduce complications, especially for higher-risk patients.
Palm Springs, CaliforniaAges 18 years+ - NCT07218627RecruitingPhase 1
Study of an investigational medicine for heart failure
This study tests an experimental medicine called NNC0537-1482 for people with heart failure. It aims to see if the medicine helps improve symptoms and heart function.
LondonAges 40–75 - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Birmingham, AlabamaAges 18–100 - NCT06659393Recruiting
Entresto in children with chronic heart failure
This study is for children with chronic heart failure who are starting Entresto for the first time. It helps doctors learn how well the medicine works and how safe it is for kids.
Ōbu, Aichi-kenAges 1–17 - NCT05553886RecruitingPhase 3
Tablets for chronic heart failure with low pumping strength
This Phase 3 study tests whether S086 tablets can improve treatment for people with chronic heart failure where the heart pumps weakly. You may be eligible if your heart failure symptoms are moderate to severe and your condition is stable on current medicines, but not if you’ve recently had certain heart events or can’t take related blood-pressure/heart drugs.
Shenzhen, GuangdongAges 18 years+ - NCT05255172Enrolling by invitation
Exercise program for heart failure with preserved or reduced pumping
This trial tests whether a structured exercise program can help people with heart failure. It focuses on people who are currently not very active, aiming to improve symptoms and heart/fitness measures safely.
LundAges 50–90 - NCT04441203Recruiting
Virtual clinic for managing heart failure at home
This trial tests a virtual “heart failure clinic” and home heart monitoring to help people manage symptoms and outcomes. It may help by catching problems earlier and guiding safer self-care between doctor visits.
Montreal, QuebecAges 18 years+ - NCT05089162Recruiting
Testing a heart ultrasound approach in chronic heart failure
This study looks at people with chronic heart failure with weaker pumping function and checks how well a lung/heart ultrasound can assess congestion (fluid buildup). If you qualify, you may help test a better way to evaluate your condition during a planned hospital visit.
Vandœuvre-lès-NancyAges 18 years+ - NCT06149195Enrolling by invitation
Heart scan for managing heart failure
This trial tests a special heart scan (18F-MFBG) to see if it can help doctors better manage heart failure. You may qualify if you have chronic heart failure with a weak heart pump and are planning to get a defibrillator.
Chengdu, SichuanAges 18–80 - NCT05089149Recruiting
Check how lung ultrasound helps manage heart failure congestion
This study looks at people with long-term worsening heart failure who are coming to the hospital for a planned visit, to see how checking “congestion” (fluid buildup) may guide care. It may help the team understand whether lung ultrasound can better assess who needs treatment changes.
Vandœuvre-lès-NancyAges 18 years+ - NCT05097898Recruiting
Check fluid buildup in heart failure with normal pumping
This study evaluates how well doctors can assess “fluid congestion” in people with chronic heart failure where the heart’s squeezing is still preserved. It may help improve how patients are monitored during hospital visits.
Vandœuvre-lès-NancyAges 18 years+ - NCT05666518Recruiting
Study of vericiguat safety in Japanese chronic heart failure patients
This study checks how safe the medicine vericiguat is for Japanese people with chronic heart failure when used in everyday care. It compares patients who receive vericiguat with patients who continue standard treatments without vericiguat.
Multiple Locations, Many LocationsAges Any age - NCT07101289Recruiting
Eat Well Heart Failure Coaching Study
This study is testing a virtual health coaching program that helps people with heart failure eat better when they have trouble affording food. The program may help prevent future hospital stays and improve your health.
Durham, North CarolinaAges 18 years+ - NCT06683001Recruiting
National heart failure registry
This study is creating a registry of people with chronic heart failure to better understand the condition. If you have any stage of chronic heart failure, you may be able to join.
MoscowAges 18 years+ - NCT07518030Recruiting
Telemedicine support for heart failure medication adjustment
This study tests whether remote check-ins via phone or video can help safely increase heart failure medications to target doses. You'll use a device to share weight, blood pressure, and heart rate with your doctor, who will adjust your medicines based on how you're doing.
PiacenzaAges 18 years+
Hear when a new Chronic Heart Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Chronic Heart Failure trials by city
Studies with a site in or near these metro areas.
Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 399 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.