Clin2
NCT05977803Possibly a fitRecruiting

MRI study of brain radiation injury in lung cancer

Brain MetastasesRadionecrosisPulmonary Cancer

Part of Brain & nervous system, Cancer, Lungs & breathing clinical trials.

This study looks at how a specific kind of MRI picture (called the CEST sequence) can help characterize radiation-related brain injury and changes in brain metastases from lung cancer. It may help doctors better interpret follow-up scans after radiation, without changing your cancer treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be older than 18 years
  • Have lung cancer confirmed by tissue biopsy (histology)
  • Have brain metastases (confirmed by tissue if available) from the lung, or suspected/known brain metastases
  • Have received radiation to the brain metastases (whole brain or focused treatments like stereotactic/gamma-knife)
  • Have had a follow-up brain MRI showing growth or worsening of one or more brain lesions

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04833335Recruiting
MRI scans to tell tumor spread from radiation injury

This trial studies how a special MRI can help doctors tell whether brain lesions after Gamma Knife treatment are growing tumors or radiation injury. It may help you avoid unnecessary treatment if the findings suggest radionecrosis instead of progression.

Paris
NCT07632092Recruiting
Brain Imaging Study After Radiotherapy for Cancer Spread

This study uses a special type of brain scan (PET imaging) to better understand how cancer that has spread to the brain responds to radiation treatment. The scan may help doctors see which patients are responding well to treatment.

Amiens
NCT05559853Recruiting
MRI scan study to track brain tumor changes after treatment

This study tests a new MRI (brain scan) method to see how brain tumors change over time after treatment. There are also parts for healthy adults to help with developing and comparing the scan technique.

New York, New York
NCT06101069Recruiting
New MRI scan to tell tumor from radiation damage

This study tests a special MRI technique to better distinguish between tumor regrowth and radiation-related changes in people with brain tumors. If you've had radiation for a brain tumor and now have suspicious changes, this scan might help guide your next steps.

Cleveland, Ohio
NCT05692635Recruiting· Phase 2
Brain MRI checks to prevent lung cancer brain symptoms

This trial tests whether doing scheduled brain MRI scans can lower the chance that lung cancer later causes symptomatic brain metastases (tumors that cause symptoms in the brain). If you’re eligible, you’ll get brain MRI surveillance at a specific time after starting radiation.

Winston-Salem, North Carolina
NCT04073966Recruiting
MRI markers for memory changes after brain radiation

This study uses MRI scans to look at how radiation treatment for newly diagnosed brain metastases affects thinking and memory. It aims to understand the effects better, which may help guide future treatment.

Chapel Hill, North Carolina

Hear when a new Brain Metastases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.