Umbilical cord patch for spina bifida repair before birth
Part of Brain & nervous system, Genetic & congenital clinical trials.
This study tests whether a patch made from donated umbilical cord can help repair spina bifida in the womb using a minimally invasive fetoscopic approach. If successful, it may reduce the need for more invasive open fetal surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are pregnant with a single baby (no twins or triplets).
- You are at least 18 years old and your pregnancy is between 19 and 26 weeks when you start.
- Your baby has a confirmed spina bifida defect in the upper to mid-back, along with Chiari II malformation (a related brain condition).
- Your baby does not have other major birth defects and has normal chromosomes (genetic testing done).
- You do not have certain health issues like poorly controlled diabetes, severe obesity (BMI over 45), or a short cervix.
- You are willing to travel and follow the study's schedule, and you have a support person with you.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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