Comparing two pacemaker settings for heart failure
Part of Heart & circulation clinical trials.
This study compares two ways of programming a special pacemaker (CRT-D) to improve heart function in people with heart failure. The goal is to see if the automatic continuous AV delay optimization (Sync-AV) works better than the standard pacing method.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have an Abbott CRT-D device (a special pacemaker that coordinates heartbeats) with the Sync-AV feature.
- Your heart must be in a normal rhythm (sinus rhythm) and show a specific pattern called left bundle branch block (LBBB) on an ECG.
- Your heart's pumping function (LVEF) must be below 35%, despite taking the best medicines for your heart.
- You cannot have had a heart attack or unstable angina in the 40 days before joining, or heart surgery in the last 4 weeks.
- You cannot have permanent atrial fibrillation (an ongoing irregular heartbeat) or be in very advanced heart failure (NYHA Class IV).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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