Can fluoxetine help recovery after serious injuries?
Treatments studied
Part of Bones, joints & muscles, Injuries & trauma, Mental health clinical trials.
This study tests whether giving the antidepressant fluoxetine (Prozac) right after a traumatic injury can help improve mental and physical recovery. It is for people who have broken bones or internal injuries from an accident and may be feeling down.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Admitted to UF Health for a serious injury like a broken bone needing surgery, a broken pelvis, or chest/belly injury requiring an operation.
- Have multiple injuries or fractures, or have a score of 14 or higher on a depression questionnaire (Beck Depression Inventory).
- Not have a severe brain injury that prevents you from answering surveys.
- Not be currently taking an antidepressant like Prozac or Zoloft.
- Not be pregnant or in jail, and be able to give informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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