Clin2
NCT06061692Possibly a fitNot yet recruiting

Tongxinluo capsule for memory problems linked to small vessel disease

Cerebral Small Vessel Diseases

Part of Brain & nervous system, Heart & circulation, Mental health clinical trials.

This trial tests whether the herbal capsule Tongxinluo can improve memory and thinking in people with small vessel disease, a condition that affects blood flow in the brain. Participants will receive either the capsule or a placebo (a pill with no active ingredient) for a period of time to see if it helps.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
1,052 people
Ages
50 years to 80 years
Study type
Interventional

Who can take part

  • You are between 50 and 80 years old.
  • You have had memory or thinking problems for at least 3 months.
  • Your thinking problems are not severe enough to be called dementia, but they are noticeable.
  • An MRI scan shows changes in the brain's white matter (the wiring) that are typical of small vessel disease.
  • You have not had a stroke in the last 6 months and have not been diagnosed with dementia.
  • You are willing to take the study medication and attend study visits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07271732Not yet recruiting
Blood pressure and liver yang capsules for small vessel brain disease

This trial tests whether an herbal capsule called Songling Xuemaikang can help people with brain changes caused by small vessel disease, such as white matter lesions or small strokes. It may improve symptoms like headache or dizziness in people with high blood pressure.

Beijing, Beijing Municipality
NCT06579664Recruiting
Brain stimulation for memory loss from small vessel disease

This trial tests whether a type of non-invasive brain stimulation called intermittent theta burst stimulation can improve memory and thinking in people whose cognitive problems are caused by cerebral small vessel disease (damage to the small blood vessels in the brain). You may qualify if you have mild memory or thinking issues that have lasted at least three months.

Beijing
NCT06673602Recruiting· Phase 4
Herbal capsule for memory problems after bleeding stroke

This trial tests a Chinese herbal capsule called Fufang Congrong Yizhi Capsule (FCYC) to see if it can help with memory and thinking problems that start after a bleeding stroke. It is for people who have had robot-assisted surgery for their stroke and also fit a specific pattern in traditional Chinese medicine.

Beijing, Beijing Municipality
NCT06507488Recruiting
Daphnetin Capsule for Mild Cognitive Issues From Blood Vessels

This trial tests a capsule called daphnetin for people with mild thinking and memory problems linked to blood vessel health. The goal is to see if it helps improve or slow down these changes.

Shenyang, Liaoning
NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease

This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.

London
NCT06112028Not yet recruiting· Phase 4
Tongxinluo to prevent re-narrowing after brain stent

This study tests whether a traditional Chinese medicine capsule, called Tongxinluo, can help prevent the artery from narrowing again after you've had a stent placed in your brain or neck. It aims to see if taking this capsule alongside your standard medicines reduces the chance of the stent getting blocked over time.

Hear when a new Cerebral Small Vessel Diseases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.