Clinical trials
Cerebral Small Vessel Diseases clinical trials
Below are recruiting cerebral small vessel diseases clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07042633Recruiting
Gamma brain waves and memory in small vessel disease study
This study looks at how brain waves in certain areas may affect memory in people with cerebral small vessel disease. It uses EEG, a safe way to measure brain activity, along with imaging and thinking tests, to understand why some people have memory trouble.
Beijing, Beijing MunicipalityAges 55–75 - NCT04753970RecruitingPhase 1/Phase 2
Study uses retina changes to assess blood vessel health
This study looks at the back of your eyes (the retina) to see if it reflects blood vessel health in the brain. It may help doctors find easier ways to track conditions related to small blood vessel disease.
Jacksonville, FloridaAges 18 years+ - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT04318119Recruiting
Brain scan registry for small blood vessel disease
This study is a registry that collects information and brain scan findings from adults with possible small vessel disease. It may help doctors better understand how this condition looks on scans and what it is linked to.
Fuzhou, FujianAges 18–100 - NCT04962295Recruiting
Brain MRI study for small blood vessel changes
This study builds a brain imaging biobank for people with “small blood vessel disease” seen on MRI. Your MRI results can help researchers better understand these changes and track new events over time.
BeijingAges 18 years+ - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT05356104RecruitingPhase 2
GLP-1 treatment to slow small blood-vessel brain damage
This Phase 2 study tests whether a GLP-1–like medicine can slow worsening “small vessel” disease changes in the brain and related walking and thinking problems. It aims to see if the treatment can prevent progression in people who already show early brain changes on MRI.
Wenzhou, ZhejiangAges 55–80 - NCT05473637Recruiting
Study causes of small vessel brain disease in stroke and memory issues
This trial looks at people who may have “small vessel” problems in the brain, which can cause stroke, memory trouble, walking changes, movement symptoms, or headaches. It may help researchers better understand the genetic and non-genetic causes, which could improve future diagnosis and treatment.
TaipeiAges 18 years+ - NCT05677607Recruiting
Study of brain artery narrowing and small-vessel disease
This study looks at how two types of blood vessel problems in the brain affect each other over time. It may help researchers better understand what to watch for and potentially how to improve outcomes.
Beijing, Beijing MunicipalityAges 30 years+ - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT05715710Recruiting
MRI and brain vein pattern study for memory and thinking problems
This study looks at whether certain deep brain veins seen on MRI are linked to thinking and memory problems in people with small-vessel brain disease. It compares brain scan findings with cognitive (thinking) testing to better understand what may drive cognitive dysfunction.
Zigong, SichuanAges 50–85 - NCT05734378Recruiting
Study aims to predict outcomes in small blood vessel brain disease
This trial is looking at how brain “small blood vessel disease” changes over time and what outcomes to expect. If you have certain symptoms or scan findings from this condition, your care team may compare your prognosis to help guide future treatment planning.
BernAges 16 years+ - NCT05746221Recruiting
Study inflammation and brain small-vessel disease in adults 40+
This study looks at inflammation-related changes in people with “small-vessel disease” of the brain. It will follow participants over time to understand the condition better and see how brain symptoms may change.
NijmegenAges 40 years+ - NCT05985213Recruiting
Brain blood vessel disease study at Yueyang Hospital
This study follows people with small vessel brain disease to understand how it changes over time. You may join if you've had an MRI showing this type of brain change and are able to take care of yourself daily.
ShanghaiAges 18–80 - NCT06010511Recruiting
White matter changes and brain fluid study in older adults
This study uses special MRI scans to look at white matter changes in the brain (often linked to memory problems). It may help doctors understand more about these changes in older adults visiting memory or geriatric clinics.
LeidenAges 65 years+ - NCT06031610Recruiting
Carotid artery opening study for brain health
This study tests if opening a narrowed carotid artery can reduce brain damage from small vessel disease. It may help patients with carotid artery narrowing prevent cognitive decline.
Hangzhou, ZhejiangAges 40–80 - NCT06164262Recruiting
Dementia risk study for people with small vessel disease
This study tracks people ages 30 to 60 who have signs of small vessel disease on brain MRI. It aims to understand the risk of dementia over the next 10 years, so you can get early monitoring and care.
Hangzhou, ZhejiangAges 30–60 - NCT06416371Recruiting
Eye vessel leakage study for mild stroke survivors
This study uses eye scans to see if blood vessel leakage in the retina (back of the eye) is linked to small vessel disease in the brain after a mild stroke. It may help doctors better understand and monitor this condition.
EdinburghAges 18 years+ - NCT06431711Recruiting
Eye scan study for brain small vessel disease
This study uses a special eye scan (OCTA) to check the health of tiny blood vessels in the back of the eye. It may help doctors understand small vessel disease in the brain and find easier ways to monitor it.
Hangzhou, ZhejiangAges 35 years+ - NCT06474507Recruiting
Calculus Bovis Sativus for Stroke Recovery
This study tests an investigational traditional Chinese medicine called Calculus Bovis Sativus (CBS) for people who have had an ischemic stroke or have small vessel disease in the brain. It aims to see if CBS can help recovery and is safe to use.
Wuhan, HubeiAges 18 years+ - NCT06579664Recruiting
Brain stimulation for memory loss from small vessel disease
This trial tests whether a type of non-invasive brain stimulation called intermittent theta burst stimulation can improve memory and thinking in people whose cognitive problems are caused by cerebral small vessel disease (damage to the small blood vessels in the brain). You may qualify if you have mild memory or thinking issues that have lasted at least three months.
BeijingAges 45–80 - NCT06579677Recruiting
Watching small blood vessels in the brain over time
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Beijing, Beijing MunicipalityAges 50–75 - NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
LondonAges 60–90 - NCT06674460RecruitingPhase 3
Edaravone Dexborneol tablet for stroke recovery
This trial tests a new sublingual tablet (Edaravone Dexborneol) to help people recover after a small stroke caused by disease of the small blood vessels in the brain. It aims to see if the drug can improve thinking and daily function.
BeijingAges 30–80
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Common questions
- Are there clinical trials for cerebral small vessel diseases?
- Yes. Clin2 currently lists 35 recruiting cerebral small vessel diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cerebral small vessel diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cerebral small vessel diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.