Study of ficlatuzumab plus cetuximab for advanced head and neck cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests a combination of two drugs, ficlatuzumab and cetuximab, for people with recurrent or metastatic head and neck cancer that is HPV-negative and has not responded to prior immunotherapy and chemotherapy. It aims to see if this combination can help shrink tumors or slow the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older with advanced head and neck cancer that has spread or come back.
- Your cancer must be HPV-negative (tested for p16).
- You must have tried one prior treatment with an immunotherapy (like Keytruda or Opdivo) and one with platinum chemo, and it either stopped working or you couldn't tolerate it.
- You must have at least one tumor that can be measured on a CT or MRI scan, and that tumor hasn't been treated with radiation (or if it has, it's clearly growing).
- You must be in relatively good health (able to do daily activities) and have a life expectancy of at least 12 weeks.
- You must not have had more than 2 prior treatments for advanced disease, and you cannot have had cetuximab or similar drugs before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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