Study of ficerafusp alfa with pembrolizumab for advanced head and neck cancer
Treatments studied
Part of Bones, joints & muscles, Cancer, Ear, nose & throat, Genetic & congenital, Lungs & breathing clinical trials.
This study tests a new drug called ficerafusp alfa (BCA101) combined with the immunotherapy pembrolizumab for people with advanced head and neck cancer that has not been treated before. The goal is to see if adding ficerafusp alfa helps shrink tumors better than pembrolizumab alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- Your cancer is in the mouth, throat (voice box), or lower throat, and is not caused by HPV (if it's in the oropharynx).
- You have not had any prior drug treatment for cancer that has spread or come back.
- Your tumor tests positive for a protein called PD-L1 (score of 1 or higher).
- You have not been treated with drugs that target EGFR or TGF-beta before.
- You have not had immunotherapy in the last 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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