Total Lymphoid Irradiation for Children's Stem Cell Transplant
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This trial tests a special type of radiation (total lymphoid irradiation) as part of the preparation for a stem cell transplant from a half-matched donor. It aims to make the transplant safer and more effective for children who need a transplant but don't have a fully matched sibling donor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 0 and 18 years old.
- You need a stem cell transplant and have a half-matched donor (like a parent).
- Your vital organs (like heart, lungs, liver) must be working well enough to handle the treatment.
- You must be generally active and able to carry out daily activities (score of 50 or more on the Karnofsky or Lansky scale).
- You cannot have HIV or be pregnant or nursing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way to give donor cells after a stem cell transplant to help the body accept them. It may help patients who need a transplant but don't have a perfectly matched donor.
This study tests two ways to prepare donated blood cells for children who need a stem cell transplant but don't have a perfectly matched sibling donor. The aim is to reduce side effects and improve outcomes.
This trial studies a new way to prepare adults with ALL for a stem cell transplant from a half-matched family donor. It compares two types of radiation-based conditioning to see which works better and has fewer side effects.
This trial tests different ways to manage stem cell transplants in children and young adults with acute lymphoblastic leukemia (ALL). It aims to find the best approach to improve outcomes and reduce complications.
This trial tests a special bone marrow/stem cell transplant approach using a partially matched family donor, along with conditioning treatment that involves radiation. It aims to help treat certain blood cancers by replacing damaged blood-forming cells with new ones from the donor.
This trial tests a stem cell transplant using a half-matched family donor for children with acute lymphoblastic leukemia (ALL) that is in remission. It compares two different types of radiation conditioning to prepare the body for the new cells, with the goal of improving outcomes.
Hear when a new Hematopoietic Organs; Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.