Microbes and spine health: a surgical study
Part of Bones, joints & muscles, Infections clinical trials.
This study looks at whether certain microbes (tiny living things) are linked to spine problems like herniated discs or narrow spinal canals. It involves people who need spine surgery, and the findings might help explain why some spines wear out faster.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have symptoms and scans showing a spine condition like a herniated disc, narrow spinal canal, or a slipped vertebra.
- You tried at least 3 months of nonsurgical treatments (like physical therapy or medication) and they didn't help enough.
- You are scheduled for spine surgery, during which a small piece of disc material will be collected.
- You do not have an active infection, metal allergy, or a mental health condition that would affect study participation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two different surgical techniques – one using a small camera (endoscopic discectomy) and the other a traditional open approach (microdiscectomy) – to treat narrowing in the lower spine. It helps find which method may be better for relieving pain and improving function.
This trial looks at whether a specific bacteria, Cutibacterium acnes, is linked to disc problems in the lower back. If you're having surgery for a herniated disc, your tissue sample may help researchers understand the cause.
This trial studies how certain chemicals in your body and brain change after a type of back surgery called endoscopic decompression. If you have lumbar spinal stenosis (narrowing of the spine) or a herniated disc and are scheduled for this surgery, you may be able to join.
This study looks at recovery after planned (elective) surgery for common lower-back (“lumbar”) spine problems like slipped discs, disc bulges, and narrowing of the spinal canal. You may be asked to complete online questionnaires, and the study uses your answers to understand symptoms and outcomes after surgery.
This study looks at genetic (inherited) factors that may influence bone healing in people undergoing major spine procedures. It may help researchers understand why some people heal differently and could guide better care in the future.
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
Hear when a new Lumbar Degenerative Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.