Stem cell transplant with special cell depletion for children and young adults
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a type of stem cell transplant that removes certain immune cells (alpha-beta T cells and CD19 B cells) from the donor cells. This may help prevent graft-versus-host disease and other complications in patients with blood cancers who do not have a matched sibling donor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 30 years or younger.
- You have a blood cancer that can be treated with a stem cell transplant, and you do not have a fully matched brother or sister to donate.
- You are generally well enough to undergo the transplant, with a performance score of 60% or higher.
- Your organs (like heart, lungs, kidneys, liver) are working well enough for the transplant.
- You are not pregnant or breastfeeding, and if you could become pregnant, you have a negative pregnancy test.
- You do not have HIV or an uncontrolled infection (like a serious fungal, bacterial, or viral infection).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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