Stem cell transplant using a half-matched donor for children and young adults
Part of Blood & lymphatic clinical trials.
This trial studies a type of stem cell transplant (bone marrow transplant) that uses a donor who is only half-matched to the patient, often a parent or sibling. It is for children and young adults with certain blood diseases, including sickle cell disease, thalassemia, bone marrow failure, and immune disorders. The transplant aims to replace the diseased blood-forming cells with healthy ones from the donor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 25 or younger (with some exceptions for sickle cell or thalassemia)
- You have one of the listed blood diseases or conditions
- You do not have a fully matched brother or sister or unrelated donor available, or you need a transplant urgently
- You have a half-matched donor (like a parent) or a closely matched unrelated donor who is willing to donate stem cells
- Your organs (kidneys, liver, heart, lungs) are working well enough
- You are not pregnant and, if of reproductive age, you agree to use birth control
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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