CyBorD plus Daratumumab for kidney disease caused by abnormal proteins
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests a combination of four drugs (CyBorD plus daratumumab) to treat kidney damage caused by abnormal proteins (monoclonal gammopathy). It aims to improve kidney function and reduce protein levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You have a kidney biopsy showing damage from abnormal proteins, or certain signs of kidney disease related to multiple myeloma.
- Your kidney function is moderately to severely reduced (eGFR below 40).
- You have measurable abnormal proteins in your blood or urine.
- You have not had prior treatment for the plasma cell condition causing the kidney problem.
- You are willing to use effective contraception if you are of childbearing potential.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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