Clin2
NCT06101108Possibly a fitRecruiting

Early heart screening in back surgery patients

Transthyretin Amyloid Cardiomyopathy

Part of Bones, joints & muscles, Heart & circulation clinical trials.

This trial checks people having back surgery for spinal stenosis to see if they have an early sign of heart amyloidosis (a protein buildup in the heart). The goal is to find this condition early so it can be treated before it causes problems.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
400 people
Ages
60 years and older
Study type
Observational

Who can take part

  • You are 60 years old or older.
  • You have lumbar spinal stenosis (a narrowing in your lower back) and are having surgery for it.
  • Your spine biopsy shows a specific type and amount of abnormal protein (called ATTR amyloid).
  • You have not been diagnosed with cardiac amyloidosis (a protein buildup in the heart) before.
  • You are willing to give informed consent to participate.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07170306Not yet recruiting
Heart stiffness and valve disease study

This study looks at whether people with both severe aortic valve narrowing and cardiac amyloidosis (a buildup of abnormal proteins in the heart) can benefit from a valve replacement procedure. It may help doctors understand how common this combination is and how to improve care.

NCT07690436Recruiting
Eye imaging for detecting a type of heart disease

This study uses retinal imaging (pictures of the back of the eye) and OCT scans to look for signs of a specific heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). It may help doctors find this condition with an eye exam instead of more invasive tests.

Palo Alto, California
NCT04849754Recruiting
Monitoring heart amyloidosis with a special scan

This study looks at how a type of heart condition called transthyretin cardiac amyloidosis changes over time, using a special imaging test called a bone scan. The goal is to see if the scan can help track the disease and potentially improve care.

Lille
NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs

This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.

Beverly Hills, California
NCT07784712Not yet recruiting
Right heart biopsy during device placement to detect cardiac amyloidosis

This study tests whether taking a small tissue sample from the right side of the heart during a routine pacemaker or defibrillator procedure can help find a condition called cardiac amyloidosis, which causes stiffening of the heart muscle. It aims to improve early detection in people who already need a cardiac device and may have early signs of the disease.

NCT06527521Recruiting
Checking for amyloidosis in trauma surgery patients

This study is looking for people having planned trauma surgery to see if they have a hidden condition called amyloidosis. It may help find the disease early, especially in people with certain health risks.

Sant Pere de Ribes, Barcelona

Hear when a new Transthyretin Amyloid Cardiomyopathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.