Clin2
NCT06114667Possibly a fitRecruiting

Nasal high flow vs. mask for COPD flare-up

Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseHypercapnic AcidosisRespiratory Failure With Hypercapnia

Part of Hormones & metabolism, Lungs & breathing clinical trials.

This study compares two types of breathing support for people having a severe COPD flare-up with high carbon dioxide and acidic blood. It tests if a gentle air flow through the nose (nasal high flow) works as well as a mask (non-invasive ventilation) to help you breathe better.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
174 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are 18 or older
  • You are having a sudden worsening of COPD (called an exacerbation) and are in the emergency room
  • You are breathing fast (at least 25 breaths per minute) or using extra muscles to breathe
  • A blood test shows high carbon dioxide (greater than 45) and acidic blood (pH less than 7.35)
  • You have not already started breathing support with a mask for this episode (unless you use it at home)
  • You are able to understand and agree to take part in the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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