Clot-busting drug for disabling stroke within 4.5 hours
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a clot-busting drug called tenecteplase for people having a disabling ischemic stroke (a clot blocking blood flow to the brain). It aims to see if the drug can help improve recovery when given within 4.5 hours of symptoms starting.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a disabling stroke (not just mild symptoms like a little numbness or blurry vision).
- You arrived at the hospital within 4.5 hours of when symptoms started or when you were last seen healthy.
- You do not have any active bleeding, recent brain surgery, head injury, or bleeding disorder that would make clot-busting drugs unsafe.
- You are able to give consent (or have a family member/guardian do so) for the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a medicine that dissolves blood clots in the brain during a stroke. It aims to see if it helps patients recover better.
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
This study compares two treatment approaches for a stroke caused by a blocked brain artery: doing a procedure to remove the clot alone versus giving an IV clot-busting medicine first (tenecteplase). It aims to see which approach works better and is safest for improving recovery.
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
This trial tests whether giving a clot-busting drug (alteplase) within 4.5 hours helps people who have a mild stroke with symptoms like vision problems, facial drooping, or trouble speaking, but no weakness in an arm or leg.
This trial tests if giving a second dose of a clot-busting drug (tenecteplase) helps people who had a stroke and didn't improve much after the first dose. You must receive the second dose within 4.5 hours of your stroke symptoms starting.
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