Clin2
NCT06150898Possibly a fitRecruiting

Ketorolac and pregabalin for estrogen receptor positive breast cancer before surgery

Early-stage Breast CancerEstrogen-receptor-positive Breast Cancer

Treatments studied

Part of Cancer, Hormones & metabolism, Skin clinical trials.

This trial tests whether two medications, ketorolac (a pain reliever) and pregabalin (a nerve pain drug), can help treat estrogen receptor (ER) positive breast cancer when taken before surgery. It may offer better pain control and possibly improve cancer outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
112 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are a woman aged 18 to 70.
  • Your breast cancer is estrogen receptor (ER) positive and at least 1.5 cm in size.
  • Your cancer is stage I, II, or III (has not spread to distant organs).
  • You are scheduled for breast cancer surgery and willing to take omeprazole (a stomach acid reducer).
  • You have no history of bleeding problems, stomach ulcers, or use of NSAID pain relievers or pregabalin recently.
  • You are not pregnant, do not have certain chronic illnesses (like severe asthma, heart failure, or autoimmune disease), and are willing to use effective birth control if needed.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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