Radiation plus immunotherapy and chemo before surgery for triple-negative breast cancer
Part of Cancer, Skin clinical trials.
This trial tests combining stereotactic radiation therapy with immunotherapy (adebrelimab) and chemotherapy (nab-paclitaxel and carboplatin) before surgery for early or locally advanced triple-negative breast cancer. The goal is to see if this combination improves treatment response.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 to 75 with newly diagnosed breast cancer that has not been treated yet.
- Your cancer must be triple-negative (ER/PR negative, HER2 negative) and at an early or locally advanced stage (stage II or III).
- You must be in good general health, with an ECOG performance status of 0 or 1 (able to carry on normal activities).
- You must have measurable tumors that can be assessed by imaging.
- You must be willing to undergo radiation therapy and surgery as part of the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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