CAR T-cell therapy for children with B-cell leukemia or lymphoma
Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.
This trial tests a CAR T-cell therapy that targets CD19 on cancer cells. It is for children whose B-cell acute lymphoblastic leukemia or aggressive B-cell non-Hodgkin lymphoma has come back or not responded to other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be under 18 years old when the trial starts.
- You must weigh at least 6 kilograms (about 13 pounds).
- You must have a type of B-cell cancer that has returned or not responded to other treatments.
- You must have a good ability to perform daily activities (score of 50% or higher on the Karnofsky or Lansky scale).
- Your cancer cells must show CD19 (a protein target) on their surface, confirmed by a recent test.
- Your heart, lungs, liver, and kidneys must be working well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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