PFO closure and brain microemboli study
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This trial looks at whether closing a small hole in the heart (PFO) can reduce tiny clots traveling to the brain. It includes people who have had a stroke or migraine, and also those without symptoms but with high-risk features.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a PFO (hole in the heart) that lets through a moderate or large number of bubbles on an ultrasound test.
- You have had a stroke or mini-stroke in the last 6 months, or migraines for more than 1 year, with no other clear cause.
- If you have no symptoms, you must have a PFO with high-risk features (like doing frequent Valsalva maneuvers or having a certain heart anatomy).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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