Testing a second diuretic for heart failure patients
Part of Heart & circulation clinical trials.
This trial tests whether adding a second type of diuretic (water pill) can help people with heart failure who don't respond well to their current diuretic. It aims to find better ways to manage fluid buildup.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with heart failure.
- You haven't been in the hospital unexpectedly in the last 2 months.
- Your doctor considers your fluid levels to be stable and at a healthy weight.
- You are resistant to a specific water pill called bumetanide, based on a test.
- Your kidney function is above a certain level (eGFR over 20).
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1 study looks at why “water pills” (diuretics) like bumetanide may not remove fluid as expected in people with heart failure. The results may help clinicians improve treatment strategies for fluid control in the future.
This Phase 1 study looks at why “water pills” sometimes stop relieving fluid overload in people with heart failure. It may help researchers understand the causes of diuretic resistance and improve future treatment for fluid management.
This trial tests a device to help the kidneys remove excess fluid in people hospitalized for worsening heart failure who are not responding well to standard diuretic (water pill) therapy. It aims to improve heart and kidney function.
This trial tests a new way to adjust diuretic (water pill) doses based on urine sodium levels in patients hospitalized for worsening heart failure. The goal is to improve fluid removal and get patients home sooner.
This trial tests if a drug called rhBNP can help patients who are not responding well to standard diuretics after heart surgery. It aims to improve urine output and remove excess fluid.
This trial uses a simple urine test to see if your current water pill dose is right for you. The goal is to find the best dose to reduce symptoms and avoid hospital visits.
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.