Radiation and immunotherapy before surgery for oral cancer
Part of Cancer, Ear, nose & throat, Mouth & dental clinical trials.
This trial tests combining radiation therapy with immunotherapy and chemotherapy before surgery for advanced oral or throat cancer. The goal is to see if this approach can shrink the tumor and improve treatment outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have squamous cell carcinoma of the mouth or throat.
- Your cancer is stage III or IVa (advanced, but has not spread to distant organs).
- You are between 18 and 70 years old.
- You are in good physical health (ECOG 0 or 1).
- You have not had prior treatment with certain immunotherapies (anti-PD-1, anti-PD-L1, or anti-CTLA-4).
- You do not have active autoimmune diseases, active tuberculosis, or serious mental illness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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