Ruxolitinib and fostamatinib for steroid-resistant chronic GVHD
Treatments studied
Part of Immune system & allergy, Lungs & breathing clinical trials.
This study tests two drugs, ruxolitinib and fostamatinib, together for people with chronic graft-versus-host disease (GVHD) that hasn't responded well to steroids. The goal is to see if this combination can better control GVHD.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You've had a stem cell transplant from a donor.
- Your chronic GVHD hasn't improved or has gotten worse while on steroids.
- You haven't taken fostamatinib before for GVHD.
- Your cancer hasn't come back after transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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