Comparing two pain medicines for knee replacement
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This study compares two medicines, mirogabalin and pregabalin, to see which works better for pain after total knee replacement. It may help you find more effective pain relief after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 85 years old.
- You have arthritis in one knee and are scheduled for a total knee replacement.
- Your physical health status is classed as ASA I, II, or III (generally healthy to moderate health risk).
- Your kidney function is normal (GFR at least 60).
- You have not taken gabapentin or pregabalin in the 3 months before surgery.
- You have not had surgery on that knee before.
- You have no severe liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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