Clin2
NCT07047040Possibly a fitNot yet recruiting

Pain relief study for knee replacement surgery

Pain, PostoperativeOsteoarthritis, Knee

Treatments studied

Part of Bones, joints & muscles, Pain clinical trials.

This study tests whether giving a combination of two medicines, ketorolac and gabapentin, before surgery can help reduce pain after a total knee replacement. It may offer better pain control for patients aged 40 to 80 having one knee replaced.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
86 people
Ages
40 years to 80 years
Study type
Interventional

Who can take part

  • Must be between 40 and 80 years old
  • Must be having a total knee replacement on just one knee
  • Must not have rheumatoid arthritis
  • Must not have a history of kidney problems
  • Must agree to join the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06328062Recruiting
Comparing two pain medicines for knee replacement

This study compares two medicines, mirogabalin and pregabalin, to see which works better for pain after total knee replacement. It may help you find more effective pain relief after surgery.

Khlong Luang, Changwat Pathum Thani
NCT06557018Recruiting· Phase 4
Numbing medicine injection for knee replacement pain

This study tests a long-lasting numbing medicine (liposomal bupivacaine) injected around the knee during total knee replacement surgery. It aims to see if this medicine helps control pain and reduce the need for other painkillers after surgery.

Dezhou, Shandong
NCT06800846Enrolling by invitation· Phase 4
Pain relief after knee replacement: injection methods compared

This study compares two ways to give pain medicine during knee replacement surgery: one is injected into the bone, the other around the joint. Researchers want to see which works better and may help you recover with less pain.

Khlong Luang, Changwat Pathum Thani
NCT07330765Not yet recruiting· Phase 1/Phase 2
Pain control study for knee replacement surgery

This study tests whether a medicine called Palmitoylethanolamide (PEA), given before knee replacement surgery, can improve pain control. It might help people recover with less pain.

Asyut, Assuit
NCT07037888Recruiting· Phase 4
Ketorolac for pain after hip arthroscopy

This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).

Detroit, Michigan
NCT06513208Recruiting· Phase 4
Ketorolac for pain after lower back fusion surgery

This trial tests if a non-steroidal anti-inflammatory drug (NSAID) called ketorolac can help reduce pain after lower back fusion surgery. It is for people who are having elective surgery to fuse one or two bones in their lower back.

Towson, Maryland

Hear when a new Pain, Postoperative trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.